Google is Using Old Books and New Technology to Combat Disease
- by Michael Stillman
A recent story on the Google Research blog quickly caught my eye: Using new technology and old books to combat disease. We tend to think of old books as a source of information about the past, which they certainly are, but the headline indicated the people at Google Brain were using them to solve today's major problems.
The issue they were tackling concerned insect-borne diseases. Mosquitoes and ticks spread dangerous diseases such as malaria and lyme disease. Add to that how annoying the itching bites can be and there is good reason to seek new ways to repel these pests. The most common repellent for mosquitoes, the active ingredient in many of the repellents you find in the store, is Deet (technically, N,N-diethyl-meta-toluamide). It was discovered 80 years ago after extensive government research. However, it does have certain drawbacks, such as damaging some types of fabrics, not working with all pests, and possibly some negative effects on people.
What the Google researchers discovered was the government had carried on extensive testing in the 1940s when they selected Deet, but what they tested and what were the results was virtually impossible to find. It was stashed away in various places with no practical way to locate it all. However, these were Google researchers and they were aware that Google had scanned and preserved reams of this old stuff as part of Google Books. This allowed them to locate these old reports and review them. What they found was surprising. The government had tested thousands of potential repellents.
Exactly how Google Brain used all this data is beyond the scope of this article, which is another way of saying the computer functions and science are beyond my understanding. The computers are using AI (Artificial Intelligence) to do comparisons of promising molecules to find others that may be useful. Eventually, they came up with a list of 10 molecules that may be more effective than Deet. Further testing will be needed. Hopefully, they will find better repellents that will save lives in areas plagued by disease-bearing insects while making our picnics more pleasant.
The issue for us is old books, and the application of new technology to them. Google Books now has 40 million volumes scanned into their database. This is definitely the information age and that is a lot of data. The issue now is making connections, using the existing data to learn things no one realized was there, and applying it to questions we want to answer today. That is where AI comes in. It can “think” at computer speed, not human speed, and it can sort through voluminous amounts of data in split seconds. Perhaps you've had a chance to ask questions of, or even get stories or poems written on demand for you by ChatGPT. Maybe you have created some unique images through Stable Diffusion. What they can do with AI and data is astonishing, at least to those of us who grew up in the age of pencils and paper. They are fun to play around with, but as Google Brain is proving, AI is serious business. Combine it with data from old books and other sources, and there is no telling what you may discover.
In our own case, over the past 20 years we have put together a database of over 12.5 million records from auctions and other sources pertaining to sales of old books. It has enabled us to not only find descriptions and prices from the past, but to create a scale for estimating the current value of old prices based on an index generated strictly from book sales. We recently developed a method of using the database to estimate the value of entire collections, not just one book at a time. We can estimate how frequently a particular title is likely to come up at auction in the future. We can determine how frequently certain words are used in descriptions of a particular title. Still, there is much more to be learned, not only about books but about the interests of people at various times, and which changes predict our interests in the future. As long as the data has been accumulated, AI will enable us to learn much more than we ever dreamed possible. These are exciting times.
Forum Auctions Fine Books, Manuscripts and Works on Paper 27th March 2025
Forum, Mar. 27: Dürer (Albrecht) Hierin sind begriffen vier bücher von menschlicher Proportion, 4 parts in 1, first edition, Nuremberg, Hieronymus Andreae for Agnes Dürer, 1528. £30,000 to £40,000.
Forum, Mar. 27: Book of Hours, Use of Rome, illuminated manuscript in Latin, on vellum, 26 fine hand-painted miniatures, 17th century dark brown morocco, [Lyon], [c. 1475 and later c. 1490-1500]. £25,000 to £35,000.
Forum, Mar. 27: Brontë (Emily) The North Wind, watercolour, [1842]. £15,000 to £20,000.
Forum, Mar. 27: Titanic.- Mudd (Thomas Cupper, one of the youngest victims of the sinking of the Titanic, 1895-1912) Autograph Letter signed on board RMS Titanic to his mother, April 11th 1912. £20,000 to £30,000.
Forum Auctions Fine Books, Manuscripts and Works on Paper 27th March 2025
Forum, Mar. 27: [Austen (Jane)] Emma: A Novel, 3 vol., first edition, for John Murray, 1816. £10,000 to £15,000.
Forum, Mar. 27: Picasso (Pablo).- Ovid. Les Metamorphoses, one of 95 copies, signed by the artist, Lausanne, Albert Skira, 1931. £10,000 to £15,000.
Forum, Mar. 27: America.- Ogilby (John) America: Being the Latest, and Most Accurate Description of the New World..., all maps with vibrant hand-colouring in outline, probably by an early hand, 1671. £15,000 to £25,000.
Forum, Mar. 27: Iceland.- Geological exploration.- Bright (Dr. Richard )and Edward Bird. Collection of twenty original drawings from travels in Iceland with Henry Holland and George Mackenzie, watercolours, [1810]. £20,000 to £30,000.
Forum Auctions The Library of Barry Humphries 26th March 2025
Forum, Mar. 26: Beckford (William) [Vathek] An Arabian Tale, first (but unauthorised) edition, Lady Caroline Lamb's copy with her signature and notes, 1786. £2,000 to £3,000.
Forum, Mar. 26: Baudelaire (Charles) Les Fleurs du Mal, first edition containing the 6 suppressed poems, first issue, contemporary half black morocco, Paris, 1857. £4,000 to £6,000.
Forum, Mar. 26: Beardsley (Aubrey).- Pope (Alexander) The Rape of the Lock, one of 25 copies on Japanese vellum, Leonard Smithers, 1896. £4,000 to £6,000.
Forum, Mar. 26: Douglas (Lord Alfred) Sonnets, first edition, the dedication copy, with signed presentation inscription from the author to his wife Olive Custance, The Academy, 1909. £2,000 to £3,000.
Forum Auctions The Library of Barry Humphries 26th March 2025
Forum, Mar. 26: Crowley (Aleister) The Works..., 3 vol. in 1 (as issued)"Essay Competition" issue on India paper, signed presentation inscription from the author, 1905-07. £1,500 to £2,000.
Forum, Mar. 26: Rodin (Auguste).- Mirbeau (Octave) Le Jardin des Supplices, one of 30 copies on chine with an additional suite, bound in dark purple goatskin, Paris, 1902. £3,000 to £4,000.
Forum, Mar. 26: Pellar (Hans) Eight original book illustrations for 'Der verliebte Flamingo' [together with] a published copy of the first edition of the book, 1923. £6,000 to £8,000.
Forum, Mar. 26: Cretté (Georges, binder).- Louÿs (Pierre) Les Aventures du Roi Pausole, 2 vol., one of 99 copies, with 2 original drawings, superbly bound in blue goatskin, gilt, Paris, 1930. £3,000 to £4,000.
Sotheby's Sell Your Fine Books & Manuscripts
Sotheby’s: The Shem Tov Bible, 1312 | A Masterpiece from the Golden Age of Spain. Sold: 6,960,000 USD
Sotheby’s: Ten Commandments Tablet, 300-800 CE | One of humanity's earliest and most enduring moral codes. Sold: 5,040,000 USD
Sotheby’s: William Blake | Songs of Innocence and of Experience. Sold: 4,320,000 USD
Sotheby’s: The Declaration of Independence | The Holt printing, the only copy in private hands. Sold: 3,360,000 USD
Sotheby's Sell Your Fine Books & Manuscripts
Sotheby’s: Thomas Taylor | The original cover art for Harry Potter and the Philosopher's Stone. Sold: 1,920,000 USD
Sotheby’s: Machiavelli | Il Principe, a previously unrecorded copy of the book where modern political thought began. Sold: 576,000 GBP
Sotheby’s: Leonardo da Vinci | Trattato della pittura, ca. 1639, a very fine pre-publication manuscript. Sold: 381,000 GBP
Sotheby’s: Henri Matisse | Jazz, Paris 1947, the complete portfolio. Sold: 312,000 EUR
Swann Printed & Manuscript African Americana March 20, 2025
Swann, Mar. 20: Lot 7: Thomas Fisher, The Negro's Memorial or Abolitionist's Catechism, London, 1825. $6,000 to $9,000.
Swann, Mar. 20: Lot 78: Victor H. Green, The Negro Travelers' Green Book, New York, 1958. $20,000 to $30,000.
Swann, Mar. 20: Lot 99: Rosa Parks, Hand-written recollection of her first meeting with Martin Luther King Jr., autograph manuscript, Detroit, c. 1990s. $30,000 to $40,000.
Swann, Mar. 20: Lot 154: Frederick Douglass, Autograph statement on voting rights, signed manuscript, 1866. $20,000 to $30,000.
Swann, Mar. 20: Lot 164: W.E.B. Du Bois, What the Negro Has Done for the United States and Texas, Washington, circa 1936. $3,000 to $4,000.
Swann Printed & Manuscript African Americana March 20, 2025
Swann, Mar. 20: Lot 263: Susan Paul, Memoir of James Jackson, Boston, 1835. $6,000 to $9,000.
Swann, Mar. 20: Lot 267: Langston Hughes, Gypsy Ballads, signed translation of García Lorca's poetry, Madrid, 1937. $1,500 to $2,500.
Swann, Mar. 20: Lot 274: Malcolm X, Collection from Alex Haley's estate, 38 items, 1963-1971. $4,000 to $6,000.
Swann, Mar. 20: Lot 367: Solomon Northup, Twelve Years a Slave, Auburn, NY, 1853. $2,500 to $3,500.
Swann, Mar. 20: Lot 402: Anna Julia Cooper, A Voice from the South, Xenia, OH, 1892. $2,000 to $3,000.
Koller, Mar. 26: Wit, Frederick de. Atlas. Amsterdam, de Wit, [1680]. CHF 20,000 to 30,000
Koller, Mar. 26: Merian, Maria Sibylla. Der Raupen wunderbare Verwandelung, und sonderbare Blumennahrung. Nürnberg, 1679; Frankfurt a. M. und Leipzig, 1683. CHF 20,000 to 30,000
Koller, Mar. 26: GOETHE, JOHANN WOLFGANG VON. Faust. Ein Fragment. Von Goethe. Ächte Ausgabe. Leipzig, G. J. Göschen, 1790. CHF 7,000 to 10,000
Koller, Mar. 26: Hieronymus. [Das hochwirdig leben der außerwoelten freünde gotes der heiligen altuaeter]. Augsburg, Johann Schönsperger d. Ä., 9. Juni 1497. CHF 40,000 to 60,000.
Koller, Mar. 26: BIBLIA GERMANICA - Neunte deutsche Bibel. Nürnberg, A. Koberger, 17. Feb. 1483. CHF 40,000 to 60,000
Koller, Mar. 26: HORAE B.M.V. - Stundenbuch. Lateinische Handschrift auf Pergament, Kalendarium französisch. Nordfrankreich (Rouen?). CHF 25,000 to 40,000